Phenotypes for Ero1b Ins2 MGI:4441480 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Ero1b^{Gt(P077G11)Wrst}/Ero1b⁺ Ins2^Akita/Ins2⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6NSlc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ero1b^{Gt(P077G11)Wrst} mutation (0 available); any Ero1b mutation (32 available)
Ins2^Akita mutation (14 available); any Ins2 mutation (90 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased insulin secretion ( J:158805 )

• in the pancreas

increased circulating glucose level ( J:158805 )

• plasma glucose levels are higher than in Ins2^Akita heterozygotes

impaired glucose tolerance ( J:158805 )

• glucose intolerance is worse than in Ins2^Akita heterozygotes

endocrine/exocrine glands

small pancreatic islets ( J:158805 )

decreased insulin secretion ( J:158805 )

• in the pancreas

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24