Phenotypes for Mitf Tfe3 MGI:4455022 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mitf^Mi/Mitf^Mi Tfe3^tm1Est/Tfe3^tm1Est
Genetic Background	either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mitf^Mi mutation (3 available); any Mitf mutation (74 available)
Tfe3^tm1Est mutation (1 available); any Tfe3 mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal osteoclast morphology ( J:89821 )

• small osteoclasts

immune system

abnormal osteoclast morphology ( J:89821 )

• small osteoclasts

pigmentation

absent coat pigmentation ( J:89821 )

• white coat

skeleton

abnormal osteoclast morphology ( J:89821 )

• small osteoclasts

osteopetrosis ( J:89821 )

vision/eye

microphthalmia ( J:89821 )

integument

absent coat pigmentation ( J:89821 )

• white coat

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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