Phenotypes for Mitf Tfe3 Tfec MGI:4455023 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mitf^Mi-wh/Mitf^Mi-wh Tfe3^tm1Est/Tfe3^tm1Est Tfec^tm1Est/Tfec^tm1Est
Genetic Background	either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mitf^Mi-wh mutation (8 available); any Mitf mutation (74 available)
Tfe3^tm1Est mutation (1 available); any Tfe3 mutation (20 available)
Tfec^tm1Est mutation (0 available); any Tfec mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

absent coat pigmentation ( J:89821 )

• white coat

skeleton

osteopetrosis ( J:89821 )

• mice develop osteopetrosis similar to that observed in double Mitf^Mi-wh and Tcfe3^tm1Est mutants

vision/eye

microphthalmia ( J:89821 )

integument

absent coat pigmentation ( J:89821 )

• white coat

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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