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Phenotypes Associated with This Genotype
Genotype
MGI:4455029
cx2
Allelic
Composition
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3+
Genetic
Background
either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mitfmi-ew mutation (1 available); any Mitf mutation (74 available)
Tfe3tm1Est mutation (1 available); any Tfe3 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation

skeleton
• osteopetrosis is more severe than in Mitfmi-ew homozygotes but less severe than in double homozygotes

vision/eye

integument


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory