About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4456869
cx23
Allelic
Composition
Il6tm1Kopf/Il6tm1Kopf
Il6ratm1.2Drew/Il6ratm1.2Drew
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il6ratm1.2Drew mutation (0 available); any Il6ra mutation (35 available)
Il6tm1Kopf mutation (9 available); any Il6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit delayed re-epithelialization of small and large wounds is delayed compared to in wild-type mice
• mice exhibit deficits in the formation of granulation tissue at wounds compared with wild-type mice
• however, macroscopic wound closure rates are normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory