About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4456999
Allelic
Composition
Fbxw4Dac-2J/Fbxw4+
mdac/mdac
Genetic
Background
CBy.MRL-Fbxw4Dac-2J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxw4Dac-2J mutation (1 available); any Fbxw4 mutation (28 available)
mdac mutation (0 available); any Mdac mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• affects particularly the three middle digits, on each foot
• often the metatarsal and metacarpal bones are partially or completely missing or fused; the forefeet are more severely affected than the hindfeet
• the defects are clearly recognizable in 15-day embryos

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
split hand-foot malformation 3 DOID:0090025 OMIM:246560
J:133888


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory