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Phenotypes Associated with This Genotype
Genotype
MGI:4461251
cn6
Allelic
Composition		 Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Gli1tm3(cre/ERT2)Alj/Gli1+
Genetic
Background		 involves: 129S6/SvEvTac * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (49 available)
Gli1tm3(cre/ERT2)Alj mutation (2 available); any Gli1 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal external female genitalia morphology ( J:148515 )
• female tamoxifen-treated mice exhibit well-developed prepuce unlike wild-type female mice
• adult tamoxifen-treated mice exhibit a hyperplasic prepuce with enlarged external genitalia similar to male mice unlike wild-type female mice
• however, the scrotal/perineal region is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory