immune system
• slightly in the thymus and lymph nodes
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• maturation of double positive thymocytes to single positive thymocytes is impaired compared to in wild-type mice
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• mice exhibit a marked decrease in CD4+ T cells in the thymus compared with wild-type mice
• peripheral CD4+ T cells in the spleen and lymph node are decreased compared to in wild-type mice
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• mice exhibit a moderate decrease in CD8+ T cells in the thymus compared with wild-type mice
• peripheral CD8+ T cells in the spleen and lymph node are decreased compared to in wild-type mice
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hematopoietic system
• slightly in the thymus and lymph nodes
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• maturation of double positive thymocytes to single positive thymocytes is impaired compared to in wild-type mice
|
• mice exhibit a marked decrease in CD4+ T cells in the thymus compared with wild-type mice
• peripheral CD4+ T cells in the spleen and lymph node are decreased compared to in wild-type mice
|
• mice exhibit a moderate decrease in CD8+ T cells in the thymus compared with wild-type mice
• peripheral CD8+ T cells in the spleen and lymph node are decreased compared to in wild-type mice
|
endocrine/exocrine glands
• slightly in the thymus and lymph nodes
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