Phenotypes Associated with This Genotype

Genotype
MGI:4818489

cn10

• Allelic Composition: Slc6a9^tm1Veul/Slc6a9^tm1Veul; Tg(Gfap-cre)2Brn/?
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:161993 )

• hypotonic phenotype leads to premature death

• frequency of deaths peaks at around 3 days of age

• 20% of mice have a normal life span

muscle

hypotonia ( J:161993 )

• 80% of homozygotes show a strong hypotonic phenotype

• onset from day 1 through 10 days of age

• 20% of mice develop no phenotype