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Phenotypes Associated with This Genotype
Genotype
MGI:4818922
cx5
Allelic
Composition		 Smn1tm1Msd/Smn1tm1Msd
Tg(SMN2)11Tro/Tg(SMN2)11Tro
Genetic
Background		 B6.Cg-Tg(SMN2)11Tro Smn1tm1Msd/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smn1tm1Msd mutation (37 available); any Smn1 mutation (87 available)
Tg(SMN2)11Tro mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:159930 )
• mice die 6 days after birth

growth/size/body
weight loss ( J:159930 )
• mice start to lose weight 48 hours after birth unlike wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory