Phenotypes for Itga5 Itgav Tg(H2-K1-tsA58)6Kio MGI:4818937 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Itga5^tm2Hyn/Itga5^tm2Hyn Itgav^tm2Hyn/Itgav^tm2Hyn Tg(H2-K1-tsA58)6Kio/0
Genetic Background	involves: 129 * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga5^tm2Hyn mutation (2 available); any Itga5 mutation (47 available)
Itgav^tm2Hyn mutation (2 available); any Itgav mutation (53 available)
Tg(H2-K1-tsA58)6Kio mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell adhesion ( J:161850 )

• endothelial cells when transiently transfected with cre, have reduced adhesion to fibronectin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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