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Phenotypes Associated with This Genotype
Genotype
MGI:4833986
cx9
Allelic
Composition		 Cx3cr1tm1Litt/Cx3cr1tm1Litt
Tg(SOD1*G93A)1Gur/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cx3cr1tm1Litt mutation (6 available); any Cx3cr1 mutation (45 available)
Tg(SOD1*G93A)1Gur mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:110266 )
• decreased survival in male mice compared with Tg(SOD1*G93A)1Gur mice

nervous system
decreased neuron number ( J:110266 )
• compared with Tg(SOD1*G93A)1Gur mice

behavior/neurological
decreased grip strength ( J:110266 )
• male mice exhibit a faster decline in hindlimb grip strength than Tg(SOD1*G93A)1Gur mice

growth/size/body
increased susceptibility to weight loss ( J:110266 )
• male mice exhibit a faster decline in body weight than Tg(SOD1*G93A)1Gur mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory