Phenotypes Associated with This Genotype

Genotype
MGI:4833987

hm3

• Allelic Composition: Cx3cl1^tm1Lira/Cx3cl1^tm1Lira
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased susceptibility to dopaminergic neuron neurotoxicity ( J:110266 )

• mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exhibit more severe neuron loss compared with similarly treated wild-type mice

nervous system

increased susceptibility to dopaminergic neuron neurotoxicity ( J:110266 )

• mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exhibit more severe neuron loss compared with similarly treated wild-type mice

cellular

increased susceptibility to dopaminergic neuron neurotoxicity ( J:110266 )

• mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exhibit more severe neuron loss compared with similarly treated wild-type mice