Phenotypes Associated with This Genotype

Genotype
MGI:4838142

hm2

• Allelic Composition: Fzd2^tm1.1Nat/Fzd2^tm1.1Nat
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:165556 )

• in 50% of mice despite normal prenatal survival

nervous system

nervous system phenotype ( J:165556 )

N • olfactory bulb morphology is normal

abnormal nervous system electrophysiology ( J:165556 )

• mice exhibit reduced electro-olfactogram response to odorant stimulation compared with wild-type mice

craniofacial

cleft palate ( J:165556 )

• in 50% of mice

growth/size/body

cleft palate ( J:165556 )

• in 50% of mice

decreased body size ( J:165556 )

• in surviving mice

taste/olfaction

abnormal olfactory system physiology ( J:165556 )

• mice exhibit reduced electro-olfactogram response to odorant stimulation compared with wild-type mice

digestive/alimentary system

cleft palate ( J:165556 )

• in 50% of mice