nervous system
• in all mice, more common in the caudal neural tube
|
• cochlear hair cell defects (hair cell number and outer hair cell row 3 orientation) are modestly more severe than in Vangl2Lp heterozygotes
|
• most severe in outer hair cell row 3
|
hearing/vestibular/ear
• cochlear hair cell defects (hair cell number and outer hair cell row 3 orientation) are modestly more severe than in Vangl2Lp heterozygotes
|
• most severe in outer hair cell row 3
|
cardiovascular system
• muscular and/or membranous in mice with neural tube defects
|
embryo
• in all mice, more common in the caudal neural tube
|
craniofacial
cleft palate
(
J:165556
)
• in 50% of mice
|
digestive/alimentary system
cleft palate
(
J:165556
)
• in 50% of mice
|
growth/size/body
cleft palate
(
J:165556
)
• in 50% of mice
|