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Phenotypes Associated with This Genotype
Genotype
MGI:4838217
Allelic
Composition
Nectin1tm1Ytk/Nectin1tm1Ytk
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nectin1tm1Ytk mutation (1 available); any Nectin1 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• lower incisors are chalky white
• lower incisors display abnormal wear at the apex
• occlusal surfaces show massive wear resulting in the absence of cusps on the 2nd and 3rd molar
• smaller lower molars in keeping with smaller body size

skeleton
• lower incisors are chalky white
• lower incisors display abnormal wear at the apex
• occlusal surfaces show massive wear resulting in the absence of cusps on the 2nd and 3rd molar
• smaller lower molars in keeping with smaller body size

growth/size/body
• lower incisors are chalky white
• lower incisors display abnormal wear at the apex
• occlusal surfaces show massive wear resulting in the absence of cusps on the 2nd and 3rd molar
• smaller lower molars in keeping with smaller body size

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT cleft lip-palate-ectodermal dysplasia syndrome DOID:0060773 OMIM:225060
J:165548


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory