Phenotypes Associated with This Genotype

Genotype
MGI:4867518

• Allelic Composition: Tg(CAG-ELN*)2Zu/0
• Genetic Background: C57BL/6J-Tg(CAG-ELN*)2Zu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:166809 )

• average survival of 47 days, with a range of 7-89 days

growth/size/body

decreased body size ( J:166809 )

respiratory system

overexpanded pulmonary alveolus ( J:166809 )

emphysema ( J:166809 )

• mice develop emphysematous lung disease

respiratory distress ( J:166809 )

• severe respiratory distress

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cutis laxa		DOID:3144	OMIM:PS123700	J:166809