Analysis Tools
hematopoietic system
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• the number of committed progenitor cells in the bone marrow is decreased compared to in wild-type mice
• however, the number of primitive progenitor numbers are normal
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• 75-fold
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• mice exhibit hypocellular bone marrow compared with wild-type mice
• however, the number of primitive progenitor numbers are normal
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• pre-B colony forming units are decreased 75-fold compared to in wild-type mice
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• lymphocytes exhibit immature nuclear chromatin unlike wild-type mice
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liver/biliary system
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• mice develop zonal microvesicular hepatic steatosis unlike wild-type mice
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pale liver
(
J:71134
)
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• primary liver cells generate increased levels of superoxide compared with wild-type cells
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skeleton
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• bone marrow exhibits an increase in fat cells compared to in wild-type mice
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immune system
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• lymphocytes exhibit immature nuclear chromatin unlike wild-type mice
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