Phenotypes Associated with This Genotype

Genotype
MGI:4946081

• Allelic Composition: Fzd9^tm1Uta/Fzd9⁺
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased bone mineral density ( J:169924 )

• osteopenia

decreased trabecular bone volume ( J:169924 )

decreased compact bone thickness ( J:169924 )

• reduction in cortical thickness of femurs

decreased osteoblast cell number ( J:169924 )

abnormal bone ossification ( J:169924 )

• decrease in bone rate formation

decreased bone strength ( J:169924 )

• vertebral bodies and femora exhibit decreased biomechanical competence

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Williams-Beuren syndrome		DOID:1928	OMIM:194050	J:169924