vision/eye
• the distance between retina pigmented epithelium and the outer limiting membrane is reduced compared to in wild-type mice
|
• half the number in wild-type mice
|
• shortened at P35 and P112
|
• at P63
|
• due to necrosis
|
• at P63
|
• mildly reduced at P70
• severely depressed at P170
• continuous decline until P276
|
• severely reduced at P41
• nearly undetectable by P170
|
nervous system
• half the number in wild-type mice
|
• shortened at P35 and P112
|
• at P63
|
• due to necrosis
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
retinitis pigmentosa 4 | DOID:0110372 |
OMIM:613731 |
J:170648 |