Phenotypes Associated with This Genotype

Genotype
MGI:4948967

cn4

• Allelic Composition: Map2k7^tm1.1Twad/Map2k7^tm1.2Twad; Tg(MMTV-cre)4Mam/0; Tg(MMTV-Erbb2)1Pv/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:170904 )

• compared with control mice

neoplasm

increased mammary gland tumor incidence ( J:170904 )

• mammary gland tumor onset is earlier and tumor burden heavier than in Tg(MMTV-Erbb2)1Pv mice

increased mammary adenocarcinoma incidence ( J:170904 )

integument

increased mammary gland tumor incidence ( J:170904 )

• mammary gland tumor onset is earlier and tumor burden heavier than in Tg(MMTV-Erbb2)1Pv mice

increased mammary adenocarcinoma incidence ( J:170904 )

mammary gland hyperplasia ( J:170904 )

♀

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:170904 )

• mammary gland tumor onset is earlier and tumor burden heavier than in Tg(MMTV-Erbb2)1Pv mice

increased mammary adenocarcinoma incidence ( J:170904 )

mammary gland hyperplasia ( J:170904 )

♀