Phenotypes Associated with This Genotype

Genotype
MGI:4950054

hm1

• Allelic Composition: Ntrk3^tm1.1Tes/Ntrk3^tm1.1Tes
• Genetic Background: involves: 129S1/Sv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:171397 )

N • development of glaucoma after right eye cauterization is normal

retina ganglion cell degeneration ( J:171397 )

• retinal ganglion cell development is normal in the absence of glaucoma

• resistant to retinal ganglion cell loss during glaucoma

• 20% loss after 5 weeks of glaucoma as compared to 36% loss in controls

nervous system

retina ganglion cell degeneration ( J:171397 )

• retinal ganglion cell development is normal in the absence of glaucoma

• resistant to retinal ganglion cell loss during glaucoma

• 20% loss after 5 weeks of glaucoma as compared to 36% loss in controls