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Phenotypes Associated with This Genotype
Genotype
MGI:5009550
Allelic
Composition		 Tg(Th-MYCN)41Waw/Tg(Th-MYCN)41Waw
Genetic
Background		 involves: BALB/c * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Th-MYCN)41Waw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased neuroblastoma incidence ( J:41126 )
• homozygous mutants show increased incidence and decreased latency of neuroblastoma formation compared to hemizygous mice, with 100% of mice developing tumors at 4 months of age

nervous system
increased neuroblastoma incidence ( J:41126 )
• homozygous mutants show increased incidence and decreased latency of neuroblastoma formation compared to hemizygous mice, with 100% of mice developing tumors at 4 months of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
neuroblastoma DOID:769 J:41126

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory