Phenotypes Associated with This Genotype

Genotype
MGI:5013911

• Allelic Composition: Tg(MMTV-ERBB2*,-luc)6157Aami/0
• Genetic Background: FVB-Tg(MMTV-ERBB2*,-luc)6157Aami

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Tg(MMTV-ERBB2*,-luc)6157Aami/0 mice develop spontaneous mammary tumors

neoplasm

increased mammary gland tumor incidence ( J:172352 )

• 8 tumors at 18 weeks of age

• by 25 weeks, tumors metastasize to the lungs

increased mammary adenocarcinoma incidence ( J:172352 )

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:172352 )

• 8 tumors at 18 weeks of age

• by 25 weeks, tumors metastasize to the lungs

increased mammary adenocarcinoma incidence ( J:172352 )

integument

increased mammary gland tumor incidence ( J:172352 )

• 8 tumors at 18 weeks of age

• by 25 weeks, tumors metastasize to the lungs

increased mammary adenocarcinoma incidence ( J:172352 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
breast cancer		DOID:1612	OMIM:114480	J:172352