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Phenotypes Associated with This Genotype
Genotype
MGI:5052333
cn4
Allelic
Composition		 Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sor+
Kiss1rtm1.1(cre)Uboe/Kiss1r+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(HBEGF)Awai mutation (4 available); any Gt(ROSA)26Sor mutation (1026 available)
Kiss1rtm1.1(cre)Uboe mutation (0 available); any Kiss1r mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:173936 )
N
• diphtheria-treated mice exhibit normal ovalutory cyclicity and fertility

nervous system
decreased neuron number ( J:173936 )
• diphtheria-treated mice exhibit ablation of Kiss1r+ and gonadotrophin-releasing hormone neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory