Phenotypes Associated with This Genotype

Genotype
MGI:5086116

• Allelic Composition: Tg(AMELX*P70T)2Gibs/?
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal molar morphology ( J:122914 )

• molars have irregular chalky appearance

abnormal molar cusp morphology ( J:122914 )

• molars show marked attrition of cusps

abnormal enamel rod pattern ( J:122914 )

• molar enamel has aprismatic regions with the porosity and appearance of platelike crystallites

• males exhibit more aprismatic regions than females

abnormal tooth attrition ( J:122914 )

• molars show marked attrition of cusps

growth/size/body

abnormal molar morphology ( J:122914 )

• molars have irregular chalky appearance

abnormal molar cusp morphology ( J:122914 )

• molars show marked attrition of cusps

abnormal enamel rod pattern ( J:122914 )

• molar enamel has aprismatic regions with the porosity and appearance of platelike crystallites

• males exhibit more aprismatic regions than females

abnormal tooth attrition ( J:122914 )

• molars show marked attrition of cusps

skeleton

abnormal molar morphology ( J:122914 )

• molars have irregular chalky appearance

abnormal molar cusp morphology ( J:122914 )

• molars show marked attrition of cusps

abnormal enamel rod pattern ( J:122914 )

• molar enamel has aprismatic regions with the porosity and appearance of platelike crystallites

• males exhibit more aprismatic regions than females

abnormal tooth attrition ( J:122914 )

• molars show marked attrition of cusps

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amelogenesis imperfecta type 1E		DOID:0110058	OMIM:301200	J:122914