Phenotypes Associated with This Genotype

Genotype
MGI:5086227

cx5

• Allelic Composition: Glrb^spa/Glrb^spa; Tg(Eno2-Glrb)456Wha/Tg(Eno2-Glrb)456Wha
• Genetic Background: involves: C3HeB/FeLe * C57BL/6 * C57BL/6J * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:60037 )

N • male mice exhibit normal fertility unlike Glrb^spa homozygotes

behavior/neurological

impaired righting response ( J:60037 )

• in 14% of mice compared with 100% of Glrb^spa homozygotes

limb grasping ( J:60037 )

• in 32% of mice compared with 100% of Glrb^spa homozygotes

tremors ( J:60037 )

• between 2 and 10 days, mice exhibit transient handling-induced tremors

• after 20 to 35 days, mice exhibit tremors that are less strong than in Glrb^spa homozygotes