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Phenotypes Associated with This Genotype
Genotype
MGI:5140202
cn1
Allelic
Composition		 Jam3tm1.1Chav/Jam3tm1.1Chav
Tg(Tal1-cre/ERT)1Jrg/?
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jam3tm1.1Chav mutation (0 available); any Jam3 mutation (24 available)
Tg(Tal1-cre/ERT)1Jrg mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased metastatic potential ( J:173391 )
• B16 cell transmigration is considerably reduced after treatment with 4-hydroxytamoxifen
• significantly reduced B16 melanoma lung metastasis after treatment with 4-hydroxytamoxifen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory