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Phenotypes Associated with This Genotype
Genotype
MGI:5140826
hm1
Allelic
Composition
Trp63tm2Brd/Trp63tm2Brd
Genetic
Background
B6.129S7-Trp63tm2Brd/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63tm2Brd mutation (1 available); any Trp63 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• at P0, failure of horizontal basal cells differentiation
• at P0, axon bundles are not covered over by the arching processes of basal cells
• cells with olfactory gland morphology are clustered in the olfactory epithelium superficial to the basal lamina
• at P0, failure of horizontal basal cells differentiation
• at P0 the extension of the ducts of the olfactory glands into the lamina propria is stunted

endocrine/exocrine glands
• at P0 the extension of the ducts of the olfactory glands into the lamina propria is stunted

respiratory system
• at P0, failure of horizontal basal cells differentiation
• at P0, axon bundles are not covered over by the arching processes of basal cells
• cells with olfactory gland morphology are clustered in the olfactory epithelium superficial to the basal lamina
• at P0, failure of horizontal basal cells differentiation

craniofacial
• at P0, failure of horizontal basal cells differentiation
• at P0, axon bundles are not covered over by the arching processes of basal cells
• cells with olfactory gland morphology are clustered in the olfactory epithelium superficial to the basal lamina
• at P0, failure of horizontal basal cells differentiation

growth/size/body
• at P0, failure of horizontal basal cells differentiation
• at P0, axon bundles are not covered over by the arching processes of basal cells
• cells with olfactory gland morphology are clustered in the olfactory epithelium superficial to the basal lamina
• at P0, failure of horizontal basal cells differentiation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory