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Phenotypes Associated with This Genotype
Genotype
MGI:5285617
Allelic
Composition
Dnah5b2b016Clo/Dnah5b2b016Clo
Genetic
Background
C57BL/6J-Dnah5b2b016Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnah5b2b016Clo mutation (1 available); any Dnah5 mutation (252 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Mutant 016-030-LA presents with situs inversus totalis with dextrocardia, dextrogastria, and inverted lung and liver lobation

cardiovascular system

growth/size/body
• inverted lung lobation

renal/urinary system

respiratory system
• tracheal airway epithelium shows slow ciliary motility, with some regions of immotility
• inverted lung lobation

cellular
• tracheal airway epithelium shows slow ciliary motility, with some regions of immotility

digestive/alimentary system

liver/biliary system
• inverted liver lobation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory