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Phenotypes Associated with This Genotype
Genotype
MGI:5286081
Allelic
Composition		 Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
Genetic
Background		 (CBA/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf1tm1Tyj mutation (3 available); any Nf1 mutation (161 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm

nervous system

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
malignant astrocytoma DOID:3069 J:64364

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory