Phenotypes Associated with This Genotype

Genotype
MGI:5288598

• Allelic Composition: Nrp1^tm1.1Cruh/Nrp1^tm1.1Cruh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina blood vessel pattern ( J:176047 )

• significant increase in artery vein crossing points

• arteries are positioned anteriorly to veins in the crossing points

cardiovascular system

cardiovascular system phenotype ( J:176047 )

N • unlike in null mice, embryonic vasculogenesis and angiogenesis are normal

abnormal retina blood vessel pattern ( J:176047 )

• significant increase in artery vein crossing points

• arteries are positioned anteriorly to veins in the crossing points

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
retinal vein occlusion		DOID:1727		J:176047