Phenotypes Associated with This Genotype

Genotype
MGI:5289778

hm4

• Allelic Composition: Agrn^nmf380/Agrn^nmf380
• Genetic Background: involves: C57BL/6J * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:176117 )

• mice exhibit the same reduction in lifespan as on a coisogenic C57BL/6J background

nervous system

abnormal neuromuscular synapse morphology ( J:176117 )

• mice exhibit the same degradation of neuromuscular junction (onset and progression) as on a coisogenic C57BL/6J background

muscle

skeletal muscle atrophy ( J:176117 )

• Background Sensitivity: more severe on a C57BL/6J or DBA background than on other backgrounds