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Phenotypes Associated with This Genotype
Genotype
MGI:5289779
hm2
Allelic
Composition		 Agrnnmf380/Agrnnmf380
Genetic
Background		 involves: BALB/c * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrnnmf380 mutation (1 available); any Agrn mutation (102 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:176117 )
• mice exhibit the same reduction in lifespan as on a coisogenic C57BL/6J background

nervous system
abnormal neuromuscular synapse morphology ( J:176117 )
• mice exhibit the same degradation of neuromuscular junction (onset and progression) as on a coisogenic C57BL/6J background

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory