Phenotypes Associated with This Genotype

Genotype
MGI:5289780

hm3

• Allelic Composition: Agrn^nmf380/Agrn^nmf380
• Genetic Background: involves: C57BL/6J * CAST

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:176117 )

N • Background Sensitivity: unlike on other backgrounds, mice survive for over a year

muscle

muscle phenotype ( J:176117 )

N • Background Sensitivity: unlike on other backgrounds, mice do not exhibit significant muscle atrophy

nervous system

abnormal neuromuscular synapse morphology ( J:176117 )

• neuromuscular junctions are abnormally shaped comapred to in wild-type mice

• Background Sensitivity: severity of neuromuscular junction degradation is reduced compared to in mice on a coisogenic C57BL/6J background