Phenotypes Associated with This Genotype

Genotype
MGI:5292535

• Allelic Composition: Col2a1^M2J/Col2a1⁺
• Genetic Background: B6;C3Fe-Col2a1^M2J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

A Col2a1^M2J/Col2a1⁺ mutant (left) and littermate control (right)

craniofacial

increased cranium length ( J:187363 )

• skull length is longer than normal in both males and females

cleft palate ( J:176116 , J:187363 )

short snout ( J:187363 )

digestive/alimentary system

cleft palate ( J:176116 , J:187363 )

adipose tissue

decreased percent body fat/body weight ( J:187363 )

♂

increased percent body fat/body weight ( J:187363 )

♀

growth/size/body

cleft palate ( J:176116 , J:187363 )

short snout ( J:187363 )

increased body weight ( J:187363 )

♀

skeleton

increased cranium length ( J:187363 )

• skull length is longer than normal in both males and females

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
spondyloepiphyseal dysplasia congenita		DOID:14789	OMIM:183900	J:222308