Phenotypes for Scrib Tg(Pbsn-cre)20Fwan MGI:5300202 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Scrib^tm1.1Phum/Scrib^tm1.1Phum Tg(Pbsn-cre)20Fwan/0
Genetic Background	involves: FVB/NCrl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scrib^tm1.1Phum mutation (0 available); any Scrib mutation (54 available)
Tg(Pbsn-cre)20Fwan mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

prostate gland hyperplasia ( J:178461 )

• 88% at 100 days, 75% at 200 days, and 90% at 400 days

increased prostate intraepithelial neoplasia incidence ( J:178461 )

• low-grade

abnormal prostate gland physiology ( J:178461 )

• increase in cell proliferation compared with control

neoplasm

increased prostate intraepithelial neoplasia incidence ( J:178461 )

• low-grade

endocrine/exocrine glands

prostate gland hyperplasia ( J:178461 )

• 88% at 100 days, 75% at 200 days, and 90% at 400 days

increased prostate intraepithelial neoplasia incidence ( J:178461 )

• low-grade

abnormal prostate gland physiology ( J:178461 )

• increase in cell proliferation compared with control

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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