Phenotypes for Fbn1 Tg(Tcra2C,Tcrb2C)1Dlo MGI:5301105 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fbn1^Tsk/Fbn1⁺ Tg(Tcra2C,Tcrb2C)1Dlo/?
Genetic Background	involves: C57BL/10 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn1^Tsk mutation (2 available); any Fbn1 mutation (173 available)
Tg(Tcra2C,Tcrb2C)1Dlo mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

integument phenotype ( J:57957 )

N	• dermal fibrosis fails to develop

respiratory system

emphysema ( J:57957 )

• emphysema develops as expected for heterozygous Fbn1^Tsk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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