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Phenotypes Associated with This Genotype
Genotype
MGI:5302203
Allelic
Composition
Crbntm1.1Jjh/Crbntm1.1Jjh
Tg(Camk2a-cre)T29-1Stl/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crbntm1.1Jjh mutation (1 available); any Crbn mutation (33 available)
Tg(Camk2a-cre)T29-1Stl mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal basal locomotion and anxiety-like behaviors
• mice freeze significantly less than control mice in a contextual fear conditioning task, indicating deficit it associative learning

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autosomal recessive intellectual developmental disorder DOID:0060308 OMIM:PS249500
J:179427


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory