Phenotypes Associated with This Genotype

Genotype
MGI:5304399

• Allelic Composition: Lim2^Aca47/Lim2^Aca47
• Genetic Background: C57BL/6J-Lim2^Aca47

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:179533 )

• at 20 weeks of age, lenses are smaller, less stable, and exhibit cataracts in the nuclear region compared with wild-type lenses

abnormal lens fiber morphology ( J:179533 )

• at 10 weeks of age, lens fiber layers in the equatorial outer cortex are less regularly arranged with wave-like structures and partially increased thickness compared with wild-type lens fibers

cataract ( J:179533 )

nuclear cataract ( J:179533 )

• at 20 weeks of age

small lens ( J:179533 )

• at 20 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract		DOID:83	OMIM:601371 OMIM:PS116200	J:179533