Phenotypes Associated with This Genotype

Genotype
MGI:5304472

• Allelic Composition: Tg(RP11-209M4)AGglo/0
• Genetic Background: FVB-Tg(RP11-209M4)4Gglo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

skeleton phenotype ( J:99965 )

N • mice exhibit number numbers of osteocytes and osteoclasts

decreased bone mineral density ( J:99965 )

decreased bone volume ( J:99965 )

increased bone trabecula number ( J:99965 )

• with increased trabecular separation

decreased trabecular bone thickness ( J:99965 )

abnormal bone ossification ( J:99965 )

• mice exhibit impaired bone formation rate compared with non-transgenic mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
SOST-related sclerosing bone dysplasia		DOID:0080036	OMIM:239100	J:99965