Phenotypes for Bax Ror2 MGI:5305092 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Bax^tm1Sjk/Bax^tm1Sjk Ror2^Y324C/Ror2^Y324C
Genetic Background	involves: 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bax^tm1Sjk mutation (1 available); any Bax mutation (24 available)
Ror2^Y324C mutation (0 available); any Ror2 mutation (124 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal primordial germ cell morphology ( J:179805 )

decreased primordial germ cell number ( J:179805 )

• no increase in the number of gonadal PGCs is seen compared to mutant mice wild-type for Bax

abnormal primordial germ cell migration ( J:179805 )

• increase in the number of ectopic PGCs compared to mutant mice wild-type for Bax

cellular

abnormal primordial germ cell morphology ( J:179805 )

decreased primordial germ cell number ( J:179805 )

• no increase in the number of gonadal PGCs is seen compared to mutant mice wild-type for Bax

abnormal primordial germ cell migration ( J:179805 )

• increase in the number of ectopic PGCs compared to mutant mice wild-type for Bax

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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