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Phenotypes Associated with This Genotype
Genotype
MGI:5306147
cx12
Allelic
Composition		 Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave
Tg(BCL2)22Wehi/0
Genetic
Background		 involves: C57BL/6JWehi * SJL/JWehi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-Jtm1.1Lave mutation (0 available); any Igh-J mutation (13 available)
Igk-Jtm1.1Lave mutation (0 available); any Igk-J mutation (11 available)
Tg(BCL2)22Wehi mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell differentiation ( J:179317 )
• B cell development is partially rescued

hematopoietic system
abnormal B cell differentiation ( J:179317 )
• B cell development is partially rescued

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory