Phenotypes Associated with This Genotype

Genotype
MGI:5311158

• Allelic Composition: Dnah5^b2b601Clo/Dnah5^b2b601Clo
• Genetic Background: C57BL/6J-Dnah5^b2b601Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Situs inversus totalis

cardiovascular system

right aortic arch ( J:175213 )

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

dextrocardia ( J:175213 )

• dextrocardia with double outlet right ventricle (DORV) and atrioventricular septal defect (AVSD)

mesocardia ( J:175213 )

atrioventricular septal defect ( J:175213 )

complete atrioventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

abdominal situs ambiguus ( J:175213 )

situs inversus totalis ( J:175213 )

respiratory system

immotile respiratory cilia ( J:175213 )

• immotile airway cilia with outer dynein arm defect

cellular

immotile respiratory cilia ( J:175213 )

• immotile airway cilia with outer dynein arm defect

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia 3		DOID:0110599	OMIM:608644	J:175213
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213