Phenotypes Associated with This Genotype

Genotype
MGI:5311937

• Allelic Composition: Ift74^b2b796Clo/Ift74^b2b796Clo
• Genetic Background: C57BL/6J-Ift74^b2b796Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 796-002-NA shows DORV and dual IVC confirmed by micro-CT scan

cardiovascular system

abnormal inferior vena cava morphology ( J:175213 )

• dual inferior vena cavae (IVC)

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

common atrium ( J:175213 )

atrioventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

respiratory system

abnormal respiratory system morphology ( J:175213 )

abnormal lung lobe morphology ( J:175213 )

• ambiguous lung lobation

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213