Phenotypes Associated with This Genotype

Genotype
MGI:5312933

• Allelic Composition: b2b997Clo/b2b997Clo
• Genetic Background: C57BL/6J-b2b997Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 997-006-LA shows heterotaxy indicated by mesocardia, right lung isomerism, and mid-line liver

cardiovascular system

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

d-loop transposition of the great arteries ( J:175213 )

common atrium ( J:175213 )

unbalanced complete common atrioventricular canal ( J:175213 )

• unbalanced complete common atrioventricular canal

ventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

abdominal situs ambiguus ( J:175213 )

right pulmonary isomerism ( J:175213 )

respiratory system

abnormal lung morphology ( J:175213 )

right pulmonary isomerism ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213