Phenotypes Associated with This Genotype

Genotype
MGI:5313412

cx13

• Allelic Composition: Dmd^mdx/Dmd^mdx; Mamstr^tm1.2Eno/Mamstr^tm1.2Eno
• Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal skeletal muscle satellite cell proliferation ( J:179880 )

♀ • hyperproliferative in culture

decreased skeletal muscle weight ( J:179880 )

♀ • at 4 and 6 weeks of age compared to mice homozygous for Dmd^mdx alone

skeletal muscle fibrosis ( J:179880 )

♀ • severe muscle damage and increased fibrosis

muscle degeneration ( J:179880 )

♀ • severe muscle damage and increased fibrosis

growth/size/body

decreased body weight ( J:179880 )

♀ • at 4 and 6 weeks of age compared to mice homozygous for Dmd^mdx alone

cellular

abnormal skeletal muscle satellite cell proliferation ( J:179880 )

♀ • hyperproliferative in culture