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Phenotypes Associated with This Genotype
Genotype
MGI:5318548
cn2
Allelic
Composition		 Cd1d1tm1.1Aben/Cd1d1tm1.1Aben
Tg(Itgax-cre,-EGFP)4097Ach/0
Genetic
Background		 C57BL/6-Cd1d1tm1.1Aben Tg(Itgax-cre,-EGFP)4097Ach
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd1d1tm1.1Aben mutation (1 available); any Cd1d1 mutation (36 available)
Tg(Itgax-cre,-EGFP)4097Ach mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:183087 )
N
• mice exhibit normal development and distribution of NK T cells
decreased interferon-gamma secretion ( J:183087 )
• decreased in splenic and liver NK T cells after injection of alphaGC
• absent in splenic and liver NK cells after injection of alphaGC
decreased interleukin-4 secretion ( J:183087 )
• decreased in splenic and liver NK T cells after injection of alphaGC

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory