Phenotypes for Psen1 Psen2 MGI:5427484 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Psen1^tm3.1Shn/Psen1^tm3.1Shn Psen2^tm1Haa/Psen2^tm1Haa
Genetic Background	involves: 129 * C57BL/6 * C57BL/6J * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psen1^tm3.1Shn mutation (1 available); any Psen1 mutation (61 available)
Psen2^tm1Haa mutation (0 available); any Psen2 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal spatial working memory ( J:184454 )

• mild impairment of spatial memory in a Morris water maze

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24