Phenotypes Associated with This Genotype

Genotype
MGI:5427915

• Allelic Composition: Tg(APPV717F)109Ili/0
• Genetic Background: involves: BALB/c * C57BL * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

amyloid beta deposits ( J:184975 )

behavior/neurological

abnormal spatial learning ( J:184975 )

• significant deficits in latency to find the target on the Barnes maze and use a poor maze strategy

increased locomotor activity ( J:184975 )

• increase in locomotor activity in an open field

homeostasis/metabolism

amyloid beta deposits ( J:184975 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Alzheimer's disease		DOID:10652		J:184975